Faculty Members

Dr. Shailendra S. Chaudhaery
Lecturer
Dept.of PharmacoInformatics

National Institute of Pharmaceutical Education & Research,
(NIPER), Hajipur-844 101, Bihar, India.

Ph: +91-8002834999, +91-9891747685
Email : shail12cdri@gmail.com


Educational qualifications:
Ph.D (Biotechnology): Central Drug Research Institute, Medicinal & Process Chemistry division. Lucknow, (CDRI) (CSIR Lab), India & Department of Biotechnology, Integral University, Lucknow, India (Nov 2007- April 2011)

M.Sc (Biotechnology): Kumaun University, Nanital, (Uttaranchal), India (2004)

 

Professional experience:

Research Associate: University of Hyderabad - School of Chemistry, Hyderabad, AP, India

Research Associate: Bioinformatics Division, Dr. B. R. Ambedkar Center for Biomedical Research (ACBR) University of Delhi, Delhi, India

Research Associate: School of Computational and Integrative Sciences, Jawaharlal Nehru University (JNU), New Delhi, India.

 

Fellowship

CSIR-UGC NET (JRF) fellowships in subject “Life Science” in 2004

All India Combined Biotech Entrance Exam, conducted by JNU, New Delhi in July 2002.

 

Publications:

Novel Carbamates as Orally Active Acetylcholinesterase Inhibitors Found to Improve Scopolamine- Induced Cognition Impairment:Pharmacophore-Based Virtual Screening, Synthesis,and Pharmacology. Shailendra S. Chaudhaery, Kuldeep K. Roy, Neeraj Shakya, Gunjan Saxena, Shreesh Raj Sammi, Aamir Nazir, Chandishwar Nath and Anil K. Saxena, J. Med. Chem., 2010, 53 (17), 6490-6505.

Consensus Superiority of the Pharmacophore-based Alignment, Over Maximum Common Substructure a.(MCS):3D-QSAR Studies on Carbamates as Acetylcholinesterase Inhibitors. Shailendra S. Chaudhaery, Kuldeep K. Roy and Anil K. Saxena*, Journal of Chemical Information and Modeling 2009, 49 (6), 1590-1601.

16α-Hydroxycleroda-3, 13 (14) Z-dien-15, 16-olide from Polyalthia longifolia: a safe and orally active a.antileishmanial agent. Msra,Pragya1; Sashidhara, Koneni V2; Singh, Suriya Pratap2; Kumar, Awanish1; Gupta, Reema1; Chaudhaery, Shailendra S2; Gupta, Souvik Sen3; Majumder, HK3, Saxena,Anil K2; Dube1, Anuradha. British Journal of Pharmacology 2010, 159(5), 1143-1150.

Molecular Modeling and Docking Studies on Hsp90 Inhibitors. A. K. Saxenaa; S. Saxenaa; S. S. Chaudhaerya, SAR and QSAR in Environmental Research. 2010, 21, 1-20.

Pharmacophore-based virtual screening and docking studies on Hsp90 inhibitors, Saxena S, Chaudhaerya. SS, Varshney K, Saxena AK. SAR QSAR Environ Res. 2010, 21(5-6):445-62.

Cloning, overexpression and characterization of Leishmania donovani squalene synthase. Prachi Bhargava1, Kishore Kumar1, Shailendra S. Chaudhaery2, Anil K. Saxena2, Um a Roy1, FEMS Microbiology Letters. 2010, 311(1), 82-92.

N-Substituted [phenyl-pyrazolo]-oxazin-2-thiones as COX-LOX inhibitors: influence of the replacement of the oxo -group with thioxo- group on the COX inhibition activity of N-substituted pyrazolo-oxazin-2-ones .Nora Bennamane,a Bellara Nedjar-Kolli,a Athina A. Geronikaki,b* Phaedra Th. Eleftheriou,c Rachedine Kaoua,a Kamal Boubekeur,d Pascal Hoffman,e Shailendra S. Chaudhary,f and Anil K. Saxena f. ARKIVOC., 2011, (ii) 69-82

 

Poster Presented

Pharmacophore Identification and Docking Studies on Hsp90 Inhibitors; Shailendra S. Chaudhaery, Anil K.Saxena; presented in International conference & Humboldt kolleg, Lucknow in 2010.

Development of 3D-Pharamacophore Model as virtual screening tool for novel bradykinin B2 receptor antagonists; Shailendra S. Chaudhaery, Anil Kumar Saxena; presented in international symposium “Current Trends in Drug Discovery and Research (CTDDR)-2010, Central Drug Research Institute, Lucknow”.

“Hypogen Based Pharmacophore model Development on Structurally Diverse Carbamates as Acetylcholine esterase inhibitors”. Shailendra S. Chaudhaery, Anil Kumar Saxena.; presented in 13th International Conference on the Interface of Chemistry Biology in Biomedical Research (ISCBC)-2009, New Delhi.

“3D-QSAR of Acetylcholine esterase inhibitors for the treatment of Alzhiemer’s disease”. Shailendra S. Chaudhaery, Anil Kumar Saxena.; presented in 12th International Conference on the Interface of Chemistry Biology In Biomedical Research (ISCBC)-2008, BITS-Pilani.

QSAR Studies on dual inhibitors of AchE and serotenin transpoter as a agent for Alzhiemer’s disease; Shailendra S.Chaudhaery, Anil Kumar Saxena; presented ininternational symposium “Current Trends in Drug Discovery and Research (CTDDR)-2007, Central Drug Research Institute, Lucknow”.

 

Invited Lectures:
Invited talk: “4th Workshop on Bioinformatics and Molecular Modeling in Drug Design, January 18-20, 2012, Dr. B.R. Ambedkar Center for Biomedical Research (ACBR), University of Delhi, and Delhi, India.
 
     
     
 
     
   
       
 
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