Department of Biotechnology


Amalgamation of Biology and Technology is Biotechnology, a fast growing and evolving field in Science. The world of Biotechnology is changing rapidly and dynamically. To accommodate the students for this competitive field of science, the curriculum and syllabi is crafted accordingly. Biotechnology has application in almost every field of our life including medicine, pharmaceuticals, diagnostics, agriculture, environmental sciences, eco-friendly energy generation etc. Right from understanding the cause of disease, host pathogen interaction, progression of disease, immune system of human body, to drug discovery and drug development, biotechnology has important roles to play. The Department of Biotechnology at NIPER, Hajipur was founded in 2007 with a vision to be recognized as an academic department of international reputation and to offer cutting edge, inter-disciplinary and most-sought after courses in Biotechnology. The department has ever since demonstrated an unfailing commitment towards research and man-power development in frontier areas of integrative biology. The Department offers M.S. (Pharm.), Ph.D., and Postdoctoral research programs. The duration of M.S. (Pharm) is of four semesters out of which the last two semesters are dedicated exclusively for research project. Subjects offered in first and second semesters include Microbial Genetics, Cell Biology, Biochemistry, Biostatistics, Biochemical Engineering Fundamentals, Separation Technique, Microbiology, Analysis; Diagnostics and Cell based Screening, Molecular Biology, Immunology and Immunotechnology, Sequence Analysis, Recombinant DNA Technology and Laboratory Experience in Specialized Area. This programme covers the wide range of subjects that are important for preparing the students and enhancing their competence towards the needs of growing Pharmaceutical industry in India. The Department has been recognized as a centre of eminence in the research areas of infectious diseases, epigenetics, drug and vaccine development etc. At present three independent research groups are active at the department. The department comprises of faculty having Ph.D. from prestigious laboratories and extensive postdoctoral research experience from foreign laboratories of international repute. The Department actively participates in several national/international seminars and training programs. NIPER Hajipur receives students from all corners of the country. Our ex- students are doing well in different sectors of the pharma industries including research and development, quality control, production, marketing etc. as well as in higher education and research. They are encouraged to participate in workshops and conferences at national and international levels. All the students present seminars and progress reports on regular basis. Several of our students are doing Ph.D. in various prestigious laboratories in India and abroad.


Vision and Mission of the Department:

To create novel technologies that improve the human condition by optimizing opportunities for further training and a successful transition to a career in the biotechnology and life sciences.

To provide a quality education in pursuit of knowledge, that establishes a strong foundation for understanding developments in the rapidly advancing field of biotechnology with the development of new biochemical technologies and therapies through research and education.

To provide the nation with highly trained professional who are able to implement the scientific principles to the continuous improvement of the safe, quality and value biotechnological services and products.

Faculty

Department of Pharmacy practice


OverView

The Department Pharmacy Practice, at NIPER, HAJIPUR was established in the year 2007. The aim of the Department is to impart patient oriented pharmacy education and train the students in Pharmacy Practice on par with international standards; the primary goal of the department is to train the students preparing for careers in Pharmacy Practice including teaching and research in an academic or industrial setting or in pharmaceutical companies and government research organizations.

Courses offered

The department offers postgraduate M.Pharm. (Pharmacy Practice) and Doctoral (Pharmacy Practice) and post-Doctoral courses programmes. The Pharmacy Practice programme is run in collaboration with Mahavir Cancer Institute & Research Centre & Rajendra Memorial Research Institute of Medical Sciences (RMRIMS) in patna and promote quality education and research with Master's, Doctoral courses.

Objectives:

This course is designed to impart the basic knowledge and skills that are required to practice pharmacy including the provision of pharmaceutical care services to both healthcare professionals and patients in clinical settings.
This course aims to enable the students to understand the different treatment approaches in managing various disease conditions and optimizing drug therapy of a patient by individualizing the treatment plan through evidence-based medicines.
Provide the students an opportunity to learn drug development process especially the phases of clinical trials and also the ethical issues involved in the conduct of clinical research, designing, conducting and managing clinical trials.
The department intends to promote research and service, demonstrating excellence in professional practice and outreach. The department of pharmacy practice is committed to review the patient record and each prescription presented for supply for the purpose of promoting therapeutic appropriateness by indentifying : (i) Over utilization or under utilization (ii) Therapeutic duplication (iii) Drug-disease interactions (iv) Drug-drug interactions (v) Incorrect drug dosage or duration of drug treatment (vi) Drug-allergy interactions (vii) Correlation of availability of drugs (to avoid artificial shortage of drugs) (viii) Clinical abuse/misuse (ix) Promotion of rational drug use (x) Patient counseling.

Research Activities

Clinical and applied Therapeutics

Prescription-Event Monitoring (PEM)

Health related quality of life (HRQOL) & Clinical outcome

Causality assessment of adverse drug reactions

Pharmacovigilance

Bioavailability and Bioequivalence studies

Pharmacoepidemiology & Pharmacoeconomics

HPV and associated clinical outcomes

Evaluation of chemotherapy Induced Disease in cancer patients

Department of Pharmacology and Toxicology


Department of Pharmacology and Toxicology at NIPER, Hajipur was established in 2018. The department is research-oriented and offering training to postgraduate and PhD students to fulfil the national and international demand of trained pharmacologist. Since its inception, the department aspires to become a recognized Centre for the pharmacological and toxicological screening of products from various sources. The recent development is in the same line by the addition of a state of art laboratory with various instruments to perform basic to advance research. The department has good coordination with other research institutes namely Mahavir Cancer Institute and Research Centre, Patna, Rajendra Memorial Research Institute of Medical Sciences, Patna (previous mentor institute) and Central Drug Research Institute, Lucknow for various projects and study-related activities.


Program: MS. Pharm (Pharmacology and Toxicology) The duration of the postgraduate course is of 2 years spread over of 4 semesters, out of which the last two semesters are exclusively dedicated for the research project. The course curriculum is designed to cover the areas of the fundamental and regulatory aspect of safety, and efficacy of pharmaceutical products from herbal and synthetic sources. Subjects in first semester: Pathophysiology, General and Experimental Pharmacology, Chemotherapy of Parasitic and Microbial Infections, Separation Techniques, Biopharmaceutics and Pharmacokinetics, Biotechnology in Pharmaceutical Sciences, Biostatistics and Fundamentals of Intellectual Property (IP) and Technology Management.
Subjects in Second semester: Drug Metabolism, Pharmacological Screening and Assays, CNS and Respiratory Pharmacology, Autonomic, CVS, Blood, Renal and GI Pharmacology, Autacoid and Endocrine Pharmacology, Clinical Pharmacology, Regulatory Toxicology, Chemotherapy, Immunopharmacology. Project work in third and fourth semester: Though the research training starts from the first semester onwards, the real research experience is imparted to students by the experienced faculty of NIPER, Hajipur and nearby reputed scientists of other national institutes in the second year. Students are given the freedom to select the research area while the emphasis is given to work in the area of expertise of the faculty.

The broad area of research includes:

Pharmacological screening of products from herbal and synthetic sources

Toxicological studies of drugs and nanoformulations from herbal and synthetic sources

Pharmacokinetic study of drugs and formulation

Neuropharmacology and neurotoxicology

Anticancer studies

Radioprotection and chemoprotection

Immunopharmacology

Endothelial dysfunction

Our passing out students can seek career as follows:

Higher studies (PhD and Post-doc fellowships)

Preclinical and clinical pharmacologist in industry and research organizations

Pharmacovigilance, data analysis, regulatory toxicology, Scientific/medical writing, Market forecasting,

Various jobs in Clinical trial organizations

Academia

Department Of Pharmaceutics


Starting from Academic Session 2021.
MS. Pharm (Pharmaceutics)
Ph.D (Pharmaceutics)

Department Of Pharmaceutical Analysis


Starting from Academic Session 2021.
MS. Pharm (Pharmaceutical Analysis)
Ph.D (Pharmaceutical Analysis)


Department of Regulatory Toxicology


Welcome to the Department of Regulatory Toxicology at NIPER, Hajipur. The Department of Regulatory Toxicology was established in 2022. The department offers M.S. (Pharm.) program in Regulatory Toxicology, which aims to develop competent, 'Industry ready' professionals to cater to the ever-increasing requirements of Indian and overseas industries working in the fields of Pharmaceutical/Cosmetic/Biotechnological/Medical Device/Nutraceutical/Herbal products. The educational program will enable the students to gain knowledge, insights and skills related to the areas of National/International Regulations, Intellectual Property Rights. The program shall involve multidimensional teaching methodology comprising lectures from Regular Faculty, Industry Professionals and Government Officials to provide the students an inclusive and contemporary perspective to current regulatory scenarios.
Regular Faculty

Dr. Vipan Kumar Parihar
Associate Professor
Mobile No: 06224-277224
Email ID: vipanparihar@gmail.com

Dr. Nitesh Kumar
Assistant Professor
Mobile No: 9986281606
Email ID: niteshkumar43@gmail.com

Dr. Sanjiv Singh
Assistant Professor
Mobile No: 7389184144
Email ID: sanjivpg2006@gmail.com

Adjunct Faculty

Dr. VGM Naidu
Associate Professor, Pharmacology & Toxicology
MTech, PhD, NIPER Guwahati
Email : vgmnaidu@niperguwahati.ac.in

Research Interests :

His area of research interests are Molecular pharmacology, cancer targeted drug delivery systems, Animal cell culture and its application for cell based drug assays; Screening Indian biodiversity and Indian Systems of Medicine in search of newer compounds in the area of inflammation, arthritis, diabetes, cancer and hepatoprotective activities; Programmed cell death of cancer cell and signalling; Targeting sPLA2 enzymes for the treatment of chronic inflammatory disorders; Targeting RANKL for the treatment of inflammation and cancer induced bone disorders.

Dr. Somasundaram Arumugam
M.Pharm., PhD
NIPER Kolkata
Email: somasundaram143@gmail.com

Research Interest

Deciphering the Pharmaceuticals for Diabetes mediated NASH, Heart failure & Inflammatory bowel disease
• In our lab we majorly focus on the niche areas such as diabetes mediated NASH (Nonalcoholic steatohepatitis), where we are using in-house developed animal model to test the efficacy of various natural as well as synthetic molecules. If we can stop the progression of NASH to hepatocellular carcinoma, it will be a paradigm shift in this core area
• In heart failure, we are studying the underlying key mechanisms of atherosclerosis, thrombosis and finally the disease progression to heart failure (myocardial infarction). In the animal studies it provides the new insights in the cardiovascular segment, we are trying to develop new therapies by utilising natural products, synthetic molecules and biologic products as well.
• In the area of inflammatory bowel disease, we are looking deeply into the ultra structural changes that are happening in the animal after the induction with a chemical. In this aspect, we have few compounds in testing and we are trying to check whether these compounds are protecting the gastrointestinal lining and suppressing the pro-inflammatory cytokines that are causing the disease condition or not.
• Apart from these studies, we are working on the animal model of C. elegans, as this model has got huge appreciation in neuro-cognition studies. We are trying to check this animal model could be helpful in screening of the drugs and toxicity studies.